The veteran chef, who has proven to be a favorite on the UK version since 2017, will film the six-part series, plus a celebrity special, alongside Hollywood later this year.
The show hasn’t aired in the US since before the pandemic, with the last episode showing in January 2020.
It is now moving stations from ABC to The Roku Channel streaming service and former judge Sherry Yard will be replaced by Leith.
The news comes as a surprise after Prue recently indicated that she planned to slow down a bit, spend more time in the garden and with her grandchildren, as well as traveling with her husband.
Prue has previously said that Americans find the show very quaint.
“All of their competition programs are very aggressive and competitors put each other down and try to get ahead,” he explained.
“They can’t understand that Bake Off, or The Baking Show, has no prize other than winning. They can’t believe you can have a show without money.”
The American series, called The Great American Baking Show, has always been filmed in the UK, in the iconic big top.
Hollywood has appeared in several American versions, including with co-judge Marcela Valladolid, with whom he had an affair, and pastry chef Johnny Iuzzini, who was fired by ABC following allegations of sexual harassment. Mary Berry also appeared alongside Hollywood in two runs.
A spokeswoman for Love Productions, which makes the show for American audiences, said it would keep the same format.